N-Desethyl Sunitinib-d5 (hydrochloride)
N-Desethyl Sunitinib-d5 (hydrochloride) is a deuterated labeled N-Desethyl Sunitinib[1]. N-Desethyl Sunitinib (SU-12662) is a metabolite of sunitinib. Sunitinib is a potent, ATP-competitive VEGFR, PDGFRβ and KIT inhibitor with Ki values of 2, 9, 17, 8 and 4 nM for VEGFR -1, -2, -3, PDGFRβ and KIT, respectively[2].
Product Specifications
CAS Number
1261432-14-7
Product Name Alternative
SU-12662-d5 (hydrochloride)
UNSPSC
12352005
Target
Drug Metabolite; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C(/C(C1=C2)=C/C3=C(C(C(NCCNC([2H])([2H])C([2H])([2H])[2H])=O)=C(N3)C)C)NC1=CC=C2F.Cl
Molecular Formula
C20H19D5ClFN4O2
Molecular Weight
411.91
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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