Kallikrein 11 (Human, Recombinant)

<strong>Kallikrein 11 (Human, Recombinant)</strong>_x000D_ <strong>Catalog number:</strong> B2010273_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Volume/Weight:</strong> 10 ug_x000D_ <strong>pH:</strong> 7.4 upon reconstitution_x000D_ <strong>Supplied as:</strong> Lyophilized powder_x000D_ <strong>Appearance:</strong> Powder_x000D_ <strong>Applications:</strong> highly pure human Kallikrein 11, produced in Sf9 insect cells. This protein acts as a serine protease with a long list of physiological functions._x000D_ <strong>Storage:</strong> -20C_x000D_ <strong>Keywords:</strong> rHuKallikrein-11; TLSP; hK11; Hippostasin; Trypsin-like protease; Serine protease 20_x000D_ <strong>Grade:</strong> Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Unal D, Eroglu C, Tasdemir A, Karaman H, Kurtul N, Oguz A, Goksu SS, Kaplan_x000D_ B. Is Human Kallikrein 11 in Non-small Cell Lung Cancer Treated_x000D_ Chemoradiotherapy Associated with Survival? Cancer Res Treat. 2016_x000D_ Jan;48(1):98-105._x000D_ _x000D_ 2: Zhang X, Hwang YS. Cancer-associated fibroblast stimulates cancer cell_x000D_ invasion in an interleukin-1 receptor (IL-1R)-dependent manner. Oncol Lett. 2019_x000D_ Nov;18(5):4645-4650._x000D_ _x000D_ 3: Sano A, Sangai T, Maeda H, Nakamura M, Hasebe T, Ochiai A. Kallikrein_11_x000D_ expressed in human breast cancer cells releases insulin-like growth factor_x000D_ through degradation of IGFBP-3. Int J Oncol. 2007 Jun;30(6):1493-8._x000D_ _x000D_ 4: Diamandis EP, Okui A, Mitsui S, Luo LY, Soosaipillai A, Grass L, Nakamura T,_x000D_ Howarth DJ, Yamaguchi N. Human kallikrein 11: a new biomarker of prostate and_x000D_ ovarian carcinoma. Cancer Res. 2002 Jan 1;62(1):295-300._x000D_ _x000D_ 5: Shigemasa K, Gu L, Tanimoto H, O'Brien TJ, Ohama K. Human kallikrein gene 11_x000D_ (KLK11) mRNA overexpression is associated with poor prognosis in patients with_x000D_ epithelial ovarian cancer. Clin Cancer Res. 2004 Apr 15;10(8):2766-70._x000D_ _x000D_ 6: Diamandis EP, Borgoño CA, Scorilas A, Harbeck N, Dorn J, Schmitt M. Human_x000D_ kallikrein_11: an indicator of favorable prognosis in ovarian cancer patients._x000D_ Clin Biochem. 2004 Sep;37(9):823-9._x000D_ _x000D_ 7: Unal D, Tasdemir A, Oguz A, Eroglu C, Cihan YB, Turak EE, Karaman H, Soyuer_x000D_ S. Is human kallikrein_11 in gastric cancer treated with surgery and adjuvant_x000D_ chemoradiotherapy associated with survival? Pathol Res Pract. 2013_x000D_ Dec;209(12):779-83._x000D_ _x000D_ 8: Patsis C, Yiotakis I, Scorilas A. Diagnostic and prognostic significance of_x000D_ human kallikrein 11 (KLK11) mRNA expression levels in patients with laryngeal_x000D_ cancer. Clin Biochem. 2012 Jun;45(9):623-30._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/17671125/">9: McIntosh MW, Liu Y, Drescher C, Urban N, Diamandis EP. Validation and_x000D_ characterization of human kallikrein 11 as a serum marker for diagnosis of_x000D_ ovarian carcinoma. Clin Cancer Res. 2007 Aug 1;13(15 Pt 1):4422-8. </a>_x000D_ _x000D_ <strong>Products Related to Kallikrein 11 (Human, Recombinant) </strong> <a href="https://moleculardepot.com/product-category/Proteins/">: Proteins</a>