Bergenin

Bergenin is a cytoprotective and antioxidative polyphenol found in many medicinal plants. Bergenin has a wide spectrum activities such as hepatoprotective, antiinflammatory, immunomodulatory, antitumor, antiviral, and antifungal properties[1][2].

Product Specifications

CAS Number

[477-90-7]

Product Name Alternative

Cuscutin

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Apoptosis; Autophagy; Bacterial; Fungal; NF-κB; Virus Protease

Type

Natural Products

Related Pathways

Anti-infection; Apoptosis; Autophagy; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer; Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Bergenin.html

Purity

99.34

Solubility

DMSO : 103.3 mg/mL (ultrasonic; warming)

Smiles

OC1=C(OC)C(O)=C([C@@]2([H])[C@@](OC3=O)([H])[C@@H](O)[C@H](O)[C@@H](CO)O2)C3=C1

Molecular Formula

C14H16O9

Molecular Weight

328.27

Precautions

H315, H319, H335

References & Citations

[1]Shi X, et al. Anticancer activity of bergenin against cervical cancer cells involves apoptosis, cell cycle arrest, inhibition of cell migration and the STAT3 signalling pathway. Exp Ther Med. 2019 May;17 (5) :3525-3529.|[2]Yun J, et al. Bergenin decreases the morphine-induced physical dependence via antioxidative activity in mice. Arch Pharm Res. 2015 Jun;38 (6) :1248-54.|[3]de Oliveira CM, et al. Antinociceptive properties of bergenin. J Nat Prod. 2011 Oct 28;74 (10) :2062-8.