2,5-Dioxopyrrolidin-1-yl acrylate

2,5-Dioxopyrrolidin-1-yl acrylate (N-Succinimidyl acrylate) is a protein crosslinker. 2,5-Dioxopyrrolidin-1-yl acrylate can react with a monoclonal anti-horseradish peroxidase IgG antibody (anti-HRP) to modify lysine residues[1].

Product Specifications

CAS Number

[38862-24-7]

Product Name Alternative

N-Succinimidyl acrylate

UNSPSC

12352005

Hazard Statement

H302, H319

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/2-5-dioxopyrrolidin-1-yl-acrylate.html

Purity

99.58

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)

Smiles

O=C(C=C)ON1C(CCC1=O)=O

Molecular Formula

C7H7NO4

Molecular Weight

169.13

Precautions

H302, H319

References & Citations

[1]Okyem S, et, al. High-Affinity Points of Interaction on Antibody Allow Synthesis of Stable and Highly Functional Antibody-Gold Nanoparticle Conjugates. Bioconjug Chem. 2021 Aug 18;32 (8) :1753-1762.