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Antiproliferative agent-52

Antiproliferative agent-52 (Compound 4a) is an antiproliferative agent that exhibits significant antiproliferative activity against four human tumor cell lines (A549, A2780, SKOV3, HCC827), with IC50 values ranging from 5.83 to 8.63 nM. Antiproliferative agent-52 can be used in cancer research[1].

Product Specifications

CAS Number

2913194-20-2

UNSPSC

12352005

Target

Others

Type

Reference compound

Related Pathways

Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/antiproliferative-agent-52.html

Smiles

COC1=CC=C(N(C2=NC(Cl)=NC3=C2SC=C3)C)C=C1

Molecular Formula

C14H12ClN3OS

Molecular Weight

305.78

References & Citations

[1]Wu C, et al. Discovery and mechanistic insights into thieno [3, 2-d] pyrimidine and heterocyclic fused pyrimidines inhibitors targeting tubulin for cancer therapy[J]. European Journal of Medicinal Chemistry, 2024: 116649.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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