DiABZI-C2-NH2
DiABZI-C2-NH2, an active analogue containing a primary amine functionality, is a STING agonist[1].
Product Specifications
CAS Number
[2137975-93-8]
UNSPSC
12352005
Target
STING
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/diabzi-c2-nh2.html
Purity
96.14
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C2C(N=C(NC(C3=CC(C)=NN3CC)=O)N2CCCCN4C5=CC=C(C(N)=O)C=C5N=C4NC(C6=CC(C)=NN6CC)=O)=C1)NCCN
Molecular Formula
C36H43N13O4
Molecular Weight
721.81
References & Citations
[1]Ramanjulu JM, et al. Design of amidobenzimidazole STING receptor agonists with systemic activity [published correction appears in Nature. 2019 Jun;570 (7761) :E53]. Nature. 2018;564 (7736) :439-443.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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