VT107
VT-107, as an analogous to VT104, is an orally active and potent pan-TEAD auto-palmitoylation inhibitor. VT-107 can be used for the research of cancer[1].
Product Specifications
CAS Number
[2417718-63-7]
UNSPSC
12352005
Target
YAP
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/vt107.html
Purity
99.98
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C2C(C3=CC=C(C(F)(F)F)C=C3)=CC=CC2=C1)N[C@H](C4=NC(N)=CC=C4)C
Molecular Formula
C25H20F3N3O
Molecular Weight
435.44
References & Citations
[1]Tang TT, et al. Small Molecule Inhibitors of TEAD Auto-palmitoylation Selectively Inhibit Proliferation and Tumor Growth of NF2-deficient Mesothelioma. Mol Cancer Ther. 2021; 20 (6) :986-998.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6506526-01 0.1 mL
ZBTB7B, ID (Zinc Finger And BTB Domain-containing Protein 7B, Zinc Finger Protein 67 Homolog, Zfp-67, Zinc Finger And BTB Domain-containing Protein 15, Zinc Finger Protein Th-POK, T-helper-inducing POZ/Krueppel-like Factor, Krueppel-related Zinc Finger Pr
Ask
View Details 
MBS6506526-02 5x 0.1 mL
ZBTB7B, ID (Zinc Finger And BTB Domain-containing Protein 7B, Zinc Finger Protein 67 Homolog, Zfp-67, Zinc Finger And BTB Domain-containing Protein 15, Zinc Finger Protein Th-POK, T-helper-inducing POZ/Krueppel-like Factor, Krueppel-related Zinc Finger Pr
Ask
View Details 218632-01 100 µg
TIMM8A, Recombinant, Human, aa1-97, His-Tag (Mitochondrial Import Inner Membrane Translocase Subunit Tim8A, Deafness Dystonia Protein 1)
Ask
View Details