CK1-IN-3
CK1-IN-3 (compound 51) is a AC1 inhibitor with an IC50s 2.22 µM for CK-1δ[1][2].
Product Specifications
CAS Number
[349438-74-0]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Casein Kinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Stem Cell/Wnt
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ck1-in-3.html
Purity
99.00
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(NC1=NC2=CC=C(OC)C=C2S1)CC3=CC=CC=C3OC
Molecular Formula
C17H16N2O3S
Molecular Weight
328.39
Precautions
H302, H315, H319
References & Citations
[1]Ana MARTÍNEZ GIL, et al. Substituted benzothiazoles and therapeutic uses thereof for the treatment of human diseases. WO2014114825A1.|[2]Salado IG, et al. Protein kinase CK-1 inhibitors as new potential drugs for amyotrophic lateral sclerosis. J Med Chem. 2014 Mar 27;57 (6) :2755-72.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CK1
Available Sizes
Curated Selection
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