CK1-IN-3

CK1-IN-3 (compound 51) is a AC1 inhibitor with an IC50s 2.22 µM for CK-1δ[1][2].

Product Specifications

CAS Number

[349438-74-0]

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

Casein Kinase

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Stem Cell/Wnt

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ck1-in-3.html

Purity

99.00

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(NC1=NC2=CC=C(OC)C=C2S1)CC3=CC=CC=C3OC

Molecular Formula

C17H16N2O3S

Molecular Weight

328.39

Precautions

H302, H315, H319

References & Citations

[1]Ana MARTÍNEZ GIL, et al. Substituted benzothiazoles and therapeutic uses thereof for the treatment of human diseases. WO2014114825A1.|[2]Salado IG, et al. Protein kinase CK-1 inhibitors as new potential drugs for amyotrophic lateral sclerosis. J Med Chem. 2014 Mar 27;57 (6) :2755-72.