Cytokeratin 8 Antibody (Highly Pure)

<strong>Cytokeratin 8 Antibody</strong>_x000D_ <strong>Catalog number:</strong> B2010439_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 uL_x000D_ <strong>Molecular Weight or Concentration:</strong> 150 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Appearance:</strong> Clear Solution_x000D_ <strong>Applications:</strong> highly specific monoclonal antibody to human CK8 (Cytokeratin-8)._x000D_ <strong>Storage:</strong> -20C_x000D_ <strong>Keywords:</strong> Cytokeratin-8 antibody_x000D_ <strong>Grade:</strong> Biotechnology grade. All solid components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Dobashi N, Fujita J, Ohtsuki Y, Yamadori I, Yoshinouchi T, Kamei T, Tokuda M,_x000D_ Hojo S, Okada H, Takahara J. Detection of anti-cytokeratin 8 antibody in the_x000D_ serum of patients with cryptogenic fibrosing alveolitis and pulmonary fibrosis_x000D_ associated with collagen vascular disorders. Thorax. 1998 Nov;53(11):969-74._x000D_ _x000D_ 2: Bozza WP, Zhang Y, Zhang B. Cytokeratin 8/18 protects breast cancer cell_x000D_ lines from TRAIL-induced apoptosis. Oncotarget. 2018 May 1;9(33):23264-23273._x000D_ _x000D_ 3: Hsu JD, Yao CC, Lee MY, Kok LF, Wang PH, Tyan YS, Han CP. True cytokeratin_x000D_ 8/18 immunohistochemistry is of no use in distinguishing between primary_x000D_ endocervical and endometrial adenocarcinomas in a tissue microarray study. Int J_x000D_ Gynecol Pathol. 2010 May;29(3):282-9._x000D_ _x000D_ 4: Dobashi N, Fujita J, Ohtsuki Y, Yamadori I, Yoshinouchi T, Kamei T, Tokuda M,_x000D_ Hojo S, Bandou S, Ueda Y, Takahara J. Circulating cytokeratin 8:anti-cytokeratin_x000D_ 8 antibody immune complexes in sera of patients with pulmonary fibrosis._x000D_ Respiration. 2000;67(4):397-401._x000D_ _x000D_ 5: Lin WL, Chen FL, Kuo JF, Lee MY, Han CP. Cytokeratin 8/18 monoclonal antibody_x000D_ was dissimilar to anti-cytokeratin CAM 5.2.--a comment on: "Discovery of two_x000D_ novel EWSR1/ATF1 transcripts in four chimerical transcripts-expressing clear_x000D_ cell sarcoma and their quantitative evaluation, Experimental and Molecular_x000D_ Pathology 90(2): 194-200, April 2011". Exp Mol Pathol. 2011 Aug;91(1):323-4._x000D_ _x000D_ 6: Yao CC, Tseng SW, Han CP. Monoclonal antibody CAM5.2 can detect the_x000D_ cytokeratin 8, not cytokeratin 18. Comment on: "Occult disseminated tumor cells_x000D_ in lymph nodes of patients with gastric carcinoma. A critical appraisal of_x000D_ assessment and relevance. Langenbecks Arch Surg. 2009 Jan; 394(1): 105-113."._x000D_ Langenbecks Arch Surg. 2010 Mar;395(3):291-2._x000D_ _x000D_ 7: Kodack DP, Farago AF, Dastur A, Held MA, Dardaei L, Friboulet L, von Flotow_x000D_ F, Damon LJ, Lee D, Parks M, Dicecca R, Greenberg M, Kattermann KE, Riley AK,_x000D_ Fintelmann FJ, Rizzo C, Piotrowska Z, Shaw AT, Gainor JF, Sequist LV, Niederst_x000D_ MJ, Engelman JA, Benes CH. Primary Patient-Derived Cancer Cells and Their_x000D_ Potential for Personalized Cancer Patient Care. Cell Rep. 2017 Dec_x000D_ 12;21(11):3298-3309._x000D_ _x000D_ 8: Koshi R, Mustafa Y, Perry ME. Vimentin, cytokeratin 8 and cytokeratin 18 are_x000D_ not specific markers for M-cells in human palatine tonsils. J Anat. 2001_x000D_ Dec;199(Pt 6):663-74._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/22963005/">9: Han CP, Huang YC, Lee MY, Chen EY, Wang PH, Tzeng SL, Chen CK. Anti-_x000D_ cytokeratin CAM5.2 should not be mistaken for cytokeratin 8/18 monoclonal_x000D_ antibody: comment on "spindle cell squamous cell carcinoma not expressing_x000D_ stratified but simple epithelial cytokeratin: Efficacy of simple epithelial_x000D_ cytokeratin immunoreactivity" (Tokuriki A, Kiyohara T, Kouraba S, Kumakiri M,_x000D_ Journal of Dermatology 2012; 39: 72-75). J Dermatol. 2012 Dec;39(12):1110.</a>_x000D_ _x000D_ <strong>Products Related to Cytokeratin 8 Antibody </strong> <a href="https://moleculardepot.com/product-category/Antibodies/">: Antibodies</a>