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NS-3-008 (hydrochloride)

NS-3-008 hydrochloride is an orally active transcriptional inhibitor of G0/G1 switch 2 (G0s2) with an IC50 of 2.25 μM. NS-3-008 hydrochloride can be used for chronic kidney disease[1].

Product Specifications

CAS Number

1172854-54-4

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Apoptosis; Bcl-2 Family

Type

Reference compound

Related Pathways

Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/ns-3-008-hydrochloride.html

Purity

99.67

Solubility

DMSO : 125 mg/mL (ultrasonic) |H2O : 125 mg/mL (ultrasonic)

Smiles

N=C(NCC1=CC=CC=C1)NCCCCCC.Cl

Molecular Formula

C14H24ClN3

Molecular Weight

269.81

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Matsunaga N, et al. Inhibition of G0/G1 Switch 2 Ameliorates Renal Inflammation in Chronic Kidney Disease. EBioMedicine. 2016 Nov;13:262-273.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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