NS-3-008 (hydrochloride)
NS-3-008 hydrochloride is an orally active transcriptional inhibitor of G0/G1 switch 2 (G0s2) with an IC50 of 2.25 μM. NS-3-008 hydrochloride can be used for chronic kidney disease[1].
Product Specifications
CAS Number
[1172854-54-4]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Apoptosis; Bcl-2 Family
Type
Reference compound
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ns-3-008-hydrochloride.html
Purity
99.67
Solubility
DMSO : 125 mg/mL (ultrasonic) |H2O : 125 mg/mL (ultrasonic)
Smiles
N=C(NCC1=CC=CC=C1)NCCCCCC.Cl
Molecular Formula
C14H24ClN3
Molecular Weight
269.81
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Matsunaga N, et al. Inhibition of G0/G1 Switch 2 Ameliorates Renal Inflammation in Chronic Kidney Disease. EBioMedicine. 2016 Nov;13:262-273.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
