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STAT3-IN-30

Product Specifications

UNSPSC Description

STAT3-IN-30 (compound 9c) is a STAT3 inhibitor with an EC50 of 13.8 μM[1].

Target Antigen

STAT

Type

Reference compound

Related Pathways

JAK/STAT Signaling;Stem Cell/Wnt

Applications

COVID-19-immunoregulation

Field of Research

others

Assay Protocol

https://www.medchemexpress.com/stat3-in-30.html

Smiles

O=C(O)C1=CC=C(N(CC2=CC=C(C3CCCCC3)C=C2)C(CN(CC4=C(F)C(F)=C(F)C(F)=C4F)S(=O)(C5=CC=C(C(F)(F)F)C=C5)=O)=O)C=C1O

Molecular Weight

770.69

References & Citations

[1]Eiring AM, et al. Combined STAT3 and BCR-ABL1 inhibition induces synthetic lethality in therapy-resistant chronic myeloid leukemia. Leukemia. 2015 Mar;29(3):586-597. doi: 10.1038/leu.2014.245. Epub 2014 Aug 19. Erratum in: Leukemia. 2017 May;31(5):1253-1254.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-117770/STAT3-IN-30-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-117770/

Clinical Information

No Development Reported

CAS Number

1803281-30-2

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