STAT3-IN-30

STAT3-IN-30 (compound 9c) is a STAT3 inhibitor with an EC50 of 13.8 μM[1].

Product Specifications

CAS Number

[1803281-30-2]

UNSPSC

12352005

Target

STAT

Type

Reference compound

Related Pathways

JAK/STAT Signaling; Stem Cell/Wnt

Applications

COVID-19-immunoregulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/stat3-in-30.html

Smiles

O=C(O)C1=CC=C(N(CC2=CC=C(C3CCCCC3)C=C2)C(CN(CC4=C(F)C(F)=C(F)C(F)=C4F)S(=O)(C5=CC=C(C(F)(F)F)C=C5)=O)=O)C=C1O

Molecular Formula

C36H30F8N2O6S

Molecular Weight

770.69

References & Citations

[1]Eiring AM, et al. Combined STAT3 and BCR-ABL1 inhibition induces synthetic lethality in therapy-resistant chronic myeloid leukemia. Leukemia. 2015 Mar;29 (3) :586-597. doi: 10.1038/leu.2014.245. Epub 2014 Aug 19. Erratum in: Leukemia. 2017 May;31 (5) :1253-1254.