Amyloid β-Protein (Human, 1-40) [HCl Form]

<strong>Amyloid β-Protein (Human, 1-40) [HCl Form]</strong> <strong>Catalog number:</strong> MDP0748 <strong>CAS Number: </strong>313951-59-6 <strong>Sequence: </strong>Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val <strong>Amount:</strong> 500 ug <strong>Molecular Weight:</strong> 4329.6 g/mol <strong>Supplied as:</strong> Powder <strong>Applications:</strong> molecular tool for various biochemical applications <strong>Storage:</strong> -20 °C <strong>WARNING:</strong> For in vitro Research Use Only. NOT for use on humans or animals. <strong>Grade:</strong> Biotechnology grade. All products are highly pure. <strong>References:</strong> 1: Kaneko I, Kubo T, Morimoto K. [Neurotoxicity of beta-amyloid] Nihon Yakurigaku Zasshi. 2000 Feb;115(2):67-77. 2: Garzon-Rodriguez W, Sepulveda-Becerra M, Milton S, Glabe CG. Soluble amyloid Abeta-(1-40) exists as a stable dimer at low concentrations J Biol Chem. 1997 Aug 22;272(34):21037-44. 3: Ogunruku OO, Oboh G, Passamonti S, Tramer F, Boligon AA. Capsicum annuum var. grossum (Bell Pepper) Inhibits β-Secretase Activity and β-Amyloid(1-40) Aggregation J Med Food. 2017 Feb;20(2):124-130. 4: Nichols MR, Moss MA, Reed DK, Lin WL, Mukhopadhyay R, Hoh JH, Rosenberry TL. Growth of beta-amyloid(1-40) protofibrils by monomer elongation and lateral association. Characterization of distinct products by light scattering and atomic force microscopy Biochemistry. 2002 May 14;41(19):6115-27. 5: Hamazaki H. Ca(2+)-dependent binding of human serum amyloid P component to Alzheimer's beta-amyloid peptide J Biol Chem. 1995 May 5;270(18):10392-4. 6: Walsh DM, Lomakin A, Benedek GB, Condron MM, Teplow DB. Amyloid beta-protein fibrillogenesis. Detection of a protofibrillar intermediate J Biol Chem. 1997 Aug 29;272(35):22364-72. 7: Lomakin A, Chung DS, Benedek GB, Kirschner DA, Teplow DB. On the nucleation and growth of amyloid beta-protein fibrils: detection of nuclei and quantitation of rate constants Proc Natl Acad Sci U S A. 1996 Feb 6;93(3):1125-9. 8: Miners JS, Clarke P, Love S. Clusterin levels are increased in Alzheimer's disease and influence the regional distribution of Aβ Brain Pathol. 2017 May;27(3):305-313. 9: Fezoui Y, Hartley DM, Harper JD, Khurana R, Walsh DM, Condron MM, Selkoe DJ, Lansbury PT Jr, Fink AL, Teplow DB. An improved method of preparing the amyloid beta-protein for fibrillogenesis and neurotoxicity experiments Amyloid. 2000 Sep;7(3):166-78. <a href="https://pubmed.ncbi.nlm.nih.gov/24315156">10: Matsuo K, Okamoto H, Kawai Y, Quan YS, Kamiyama F, Hirobe S, Okada N, Nakagawa S. Vaccine efficacy of transcutaneous immunization with amyloid β using a dissolving microneedle array in a mouse model of Alzheimer's disease J Neuroimmunol. 2014 Jan 15;266(1-2):1-11. </a> <br><strong>Products Related to Amyloid β-Protein (Human, 1-40) [HCl Form] can be found at</strong> <a href="https://moleculardepot.com/product-category/Peptides/"> Peptides</a>