1-Stearoyl-2-Arachidonoyl-d8-sn-Glycerol
Product Specifications
UNSPSC Description
1-Stearoyl-2-Arachidonoyl-d8-sn-Glycerol is the deuterium labeled 1-Stearoyl-2-arachidonoyl-sn-glycerol. 1-Stearoyl-2-arachidonoyl-sn-glycerol is a diacylglycerol (DAG) containing polyunsaturated fatty acids. 1-Stearoyl-2-arachidonoyl-sn-glycerol can activate PKC. 1-Stearoyl-2-arachidonoyl-sn-glycerol also can augment nonselective cation channel (NSCC) activity[1][2].
Target Antigen
Endogenous Metabolite; Isotope-Labeled Compounds; PKC; TRP Channel
Type
Isotope-Labeled Compounds
Related Pathways
Epigenetics;Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling;Others;TGF-beta/Smad
Field of Research
Neurological Disease
Solubility
10 mM in DMSO
Smiles
CCCCCCCCCCCCCCCCCC(OC[C@@H](OC(CCC/C([2H])=C([2H])\C/C([2H])=C([2H])\C/C([2H])=C([2H])\C/C([2H])=C([2H])\CCCCC)=O)CO)=O
Molecular Weight
653.06
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Song T, et, al. Inositol 1,4,5-trisphosphate activates TRPC3 channels to cause extracellular Ca2+ influx in airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2015 Dec 15;309(12):L1455-66.|[3]Madani S, et, al. Implication of acyl chain of diacylglycerols in activation of different isoforms of protein kinase C. FASEB J. 2001 Dec;15(14):2595-601.|[4]Glasmacher S, et, al. Characterization of pepcan-23 as pro-peptide of RVD-hemopressin (pepcan-12) and stability of hemopressins in mice. Adv Biol Regul. 2021 May;80:100808.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
CAS Number
2692624-31-8
Available Sizes
Curated Selection
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