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1-Stearoyl-2-Arachidonoyl-d8-sn-Glycerol

Selected Variant

HY-131897S-01

Size: 1 mg

1-Stearoyl-2-Arachidonoyl-d8-sn-Glycerol is the deuterium labeled 1-Stearoyl-2-arachidonoyl-sn-glycerol. 1-Stearoyl-2-arachidonoyl-sn-glycerol is a diacylglycerol (DAG) containing polyunsaturated fatty acids. 1-Stearoyl-2-arachidonoyl-sn-glycerol can activate PKC. 1-Stearoyl-2-arachidonoyl-sn-glycerol also can augment nonselective cation channel (NSCC) activity[1][2].

Product Specifications

CAS Number

2692624-31-8

UNSPSC

12352211

Target

Endogenous Metabolite; Isotope-Labeled Compounds; PKC; TRP Channel

Type

Isotope-Labeled Compounds

Related Pathways

Epigenetics; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; Others; TGF-beta/Smad

Field of Research

Neurological Disease

Solubility

10 mM in DMSO

Smiles

CCCCCCCCCCCCCCCCCC(OC[C@@H](OC(CCC/C([2H])=C([2H])\C/C([2H])=C([2H])\C/C([2H])=C([2H])\C/C([2H])=C([2H])\CCCCC)=O)CO)=O

Molecular Formula

C41H64D8O5

Molecular Weight

653.06

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Song T, et, al. Inositol 1,4,5-trisphosphate activates TRPC3 channels to cause extracellular Ca2+ influx in airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2015 Dec 15;309 (12) :L1455-66.|[3]Madani S, et, al. Implication of acyl chain of diacylglycerols in activation of different isoforms of protein kinase C. FASEB J. 2001 Dec;15 (14) :2595-601.|[4]Glasmacher S, et, al. Characterization of pepcan-23 as pro-peptide of RVD-hemopressin (pepcan-12) and stability of hemopressins in mice. Adv Biol Regul. 2021 May;80:100808.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Available Sizes

Price

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