Human IRAK4 Protein, His Tag
Human IRAK4 Protein, His Tag (IR4-H5546) is expressed from Baculovirus-Insect cells. It contains AA Met 1 - Ser 460 (Accession # Q9NWZ3-1) .
Product Specifications
Background
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
Specifications
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 53.4 kDa. The protein migrates as 60-65 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
Q9NWZ3-1
Expression Region
Met 1 - Ser 460
Host
Insect Cells
Target
IRAK4
Conjugation
Unconjugated
Tag
C-10xHis
Source
Human
Stability
● The product MUST be stored at -70°C or lower upon receipt; ● -70°C for 3 months under sterile conditions.
Endotoxin
1.0 EU per μg
Purity
85%
Format
Liquid
Buffer
50 mM HEPES, 300 mM NaCl, pH7.5
Additives
Glycerol
Molecular Weight
53.4 kDa
Shipping Conditions
Dry ice
Storage Conditions
-70°C
Package Size
1mg*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/IR4-H5546.pdf
Species
Human
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