BC-23
Product Specifications
Product Name Alternative
Fer-1
UNSPSC Description
BC-23 (NSC 45382) is a proteasome inhibitor. BC-23 exhibits good inhibition of CT-L activity of the proteasome and is selective for malignant over normal cells[1][2].
Target Antigen
Proteasome
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bc-23.html
Purity
97.37
Solubility
DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O=S(C1=CC=C(C=C1)NC(C2=O)=C(C(C3=C2C=CC=C3)=O)Cl)(NC4=NC=CC=C4)=O
Molecular Weight
439.87
References & Citations
[1]Lawrence HR, et, al. Synthesis and biological evaluation of naphthoquinone analogs as a novel class of proteasome inhibitors. Bioorg Med Chem. 2010 Aug 1;18(15):5576-92.|[2]Zhang Q, et, al. Enhancement of Radiation Sensitivity in Lung Cancer Cells by a Novel Small Molecule Inhibitor That Targets the β-Catenin/Tcf4 Interaction. PLoS One. 2016 Mar 25;11(3):e0152407.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-119288/BC-23-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-119288/BC-23-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
6298-15-3
Available Sizes
Curated Selection
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