Schisantherin A (Standard)
Schisantherin A (Standard) is the analytical standard of Schisantherin A. This product is intended for research and analytical applications. Schisantherin A is a dibenzocyclooctadiene lignan. Schisantherin A inhibits p65-NF-κB translocation into the nucleus by IκBα degradation.
Product Specifications
CAS Number
58546-56-8
Product Name Alternative
Gomisin-C (Standard) ; Schizantherin-A (Standard) ; Wuweizi ester-A (Standard)
UNSPSC
12352005
Target
NF-κB; Reference Standards
Type
Reference Standards
Related Pathways
NF-κB; Others
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/schisantherin-a-standard.html
Smiles
O[C@]([C@@H](C)C1)(C)[C@@H](OC(C2=CC=CC=C2)=O)C3=CC(OC)=C(OC)C(OC)=C3C4=C1C=C5OCOC5=C4OC
Molecular Formula
C30H32O9
Molecular Weight
536.57
References & Citations
[1]Ci X, et al. Schisantherin A exhibits anti-inflammatory properties by down-regulating NF-kappaB and MAPK signaling pathways in lipopolysaccharide-treated RAW 264.7 cells. Inflammation. 2010 Apr;33 (2) :126-36.|[2]Zhou E, et al. Schisantherin A protects lipopolysaccharide-induced acute respiratory distress syndrome in mice through inhibiting NF-κB and MAPKs signaling pathways. Int Immunopharmacol. 2014 Sep;22 (1) :133-40.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
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