HDAC8-IN-13
HDAC8-IN-13 is a novel histone deacetylase 8 (HDAC8) inhibitor with antiparasitic activity. HDAC8-IN-13 can effectively inhibit the acetyl-L-lysine deacetylase activity of schistosomes, affecting the parasite's infectivity. HDAC8-IN-13 can induce apoptosis and cause the death of schistosome cells. Through a specific structural basis design, HDAC8-IN-13 exhibits reduced affinity for human HDACs, thereby enhancing its selectivity[1].
Product Specifications
CAS Number
949792-00-1
UNSPSC
12352005
Hazard Statement
H302-H312-H332
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/hdac8-in-13.html
Smiles
O=C(C1=CC=C(SCCC(N2)=O)C2=C1)NO
Molecular Formula
C10H10N2O3S
Molecular Weight
238.26
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]Structural basis for the inhibition of histone deacetylase 8 (HDAC8), a key epigenetic player in the blood fluke Schistosoma mansoni
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
![p53 (TP53) Mouse Monoclonal Antibody [Clone ID: SPM589]](https://cdn.genprice.uk/products/937/68dd189e061270361e8fd7bf/imageurl/am50177pu-s.webp)
p53 (TP53) Mouse Monoclonal Antibody [Clone ID: SPM589]
![IL10 Mouse Monoclonal Antibody [Clone ID: 3C12C12]](https://cdn.genprice.uk/products/937/68dd189a061270361e8fbc5e/imageurl/am06081pu-n.webp)
IL10 Mouse Monoclonal Antibody [Clone ID: 3C12C12]
(11Beta)-21-(1-Ethoxyethoxy)-11,17-dihydroxy-pregn-4-ene-3,20-dione
