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GPR55 agonist 4

GPR55 agonist 4 (Compound 28) is a GPR55 agonist (EC50: 131 nM, and 1.41 nM for hGPR55 and rGPR55) . GPR55 agonist 4 induces β-arrestin recruitment to human GPR55[1].

Product Specifications

CAS Number

3006105-55-8

UNSPSC

12352005

Target

GPR55

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/gpr55-agonist-4.html

Purity

98.36

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C1OC2=CC=C(C3=CN=C(N[C@@H](C4=CC=C(F)C=C4)C)N=N3)C=C2N1C

Molecular Formula

C19H16FN5O2

Molecular Weight

365.36

References & Citations

[1]Hewer RC, et al. Discovery and Characterization of Novel CNS-Penetrant GPR55 Agonists. J Med Chem. 2023 Sep 28;66 (18) :12858-12876.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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