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Cephradine (Standard)

Cephradine (Standard) is the analytical standard of Cephradine. This product is intended for research and analytical applications. Cephradine (Cefradine) is a broad-spectrum and orally active cephalosporin. Cephradine is active against both gram-positive and gram-negative pathogens. Cephradine is effective in eradicating most penicillinase-producing organisms. Cephradine has been used in the research of genitourinary, gastrointestinal and respiratory tract infections, and in infections of the skin and soft tissues. Cephradine blocks solar-ultraviolet induced skin inflammation through direct inhibition of TOPK[1][2][3].

Product Specifications

CAS Number

38821-53-3

Product Name Alternative

Cefradine (Standard) ; SQ-11436 (Standard)

UNSPSC

12352005

Hazard Statement

H315-H317-H319-H334-H335

Target

Antibiotic; Bacterial; Reference Standards; TOPK

Type

Reference Standards

Related Pathways

Anti-infection; Cell Cycle/DNA Damage; Others

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/cephradine-standard.html

Smiles

O=C(C(N12)=C(C)CS[C@]2([H])[C@H](NC([C@H](N)C3=CCC=CC3)=O)C1=O)O

Molecular Formula

C16H19N3O4S

Molecular Weight

349.40

Precautions

P280-P280-P302+P352-P302+P352

References & Citations

[1]Schwinghammer TL, et al. Pharmacokinetics of cephradine administered intravenously and orally to young and elderly subjects. J Clin Pharmacol. 1990;30 (10) :893-899|[2]Caloza DL Jr, et al. Intravenous use of cephradine and cefazolin against serious infections. Antimicrob Agents Chemother. 1979;15 (1) :119-122.|[3]Fan X, et al. Cefradine blocks solar-ultraviolet induced skin inflammation through direct inhibition of T-LAK cell-originated protein kinase. Oncotarget. 2016;7 (17) :24633-24645|[4]Kang S, et al. In Vitro and In Vivo Antimicrobial Activity of Antibiotic-Conjugated Carriers with Rapid pH-Responsive Release Kinetics. Adv Healthc Mater. 2019;8 (14) :e1900247.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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