E3 Ligase Ligand-linker Conjugate 146
E3 Ligase Ligand-linker Conjugate 146 is a PROTAC E3 ubiquitin ligase ligand and linker, used for synthesizing BCPyr.
Product Specifications
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e3-ligase-ligand-linker-conjugate-146.html
Smiles
O=C([C@H]1N(C([C@@H](NC([C@@H](NC)C)=O)C(C)(C)C)=O)CC2=C(C=CC(OCC3=CN=C(CO)C=N3)=C2)C1)N[C@@H]4CCCC5=C4C=CC=C5
Molecular Formula
C36H46N6O5
Molecular Weight
642.79
References & Citations
[1]James Schiemer, et al. Snapshots and ensembles of BTK and cIAP1 protein degrader ternary complexes. Nat Chem Biol. 2021 Feb;17 (2) :152-160.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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