Anti-Mouse CD38 Antibody (NIMR5)

Anti-Mouse CD38 Antibody (NIMR5) is an anti-mouse CD38 IgG2a monoclonal antibody. Anti-Mouse CD38 Antibody (NIMR5) can activate the ERK signaling pathway and promote cell apoptosis. Anti-Mouse CD38 Antibody (NIMR5) can restore T cell function. Anti-Mouse CD38 Antibody (NIMR5) upregulates the expression of CD1d protein and enhances spleen cell proliferation, dendritic cell (DC) and natural killer T cell (NKT) expansion. Anti-Mouse CD38 Antibody (NIMR5) can be used for researches on cancer and immunology such as melanoma and colon cancer[1][2][3].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352203

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; CD1; CD38; ERK

Type

Inhibitory Antibodies

Related Pathways

Apoptosis; Immunology/Inflammation; MAPK/ERK Pathway; Stem Cell/Wnt

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-mouse-cd38-antibody-nimr5.html

Purity

95.00

Solubility

10 mM in DMSO

Smiles

[Anti-MouseCD38Antibody(NIMR5)]

Molecular Weight

(150 kDa)

Precautions

H302, H315, H319, H335

References & Citations

[1]Romero-Ramírez H, et al. CD38 expression in early B-cell precursors contributes to extracellular signal-regulated kinase-mediated apoptosis. Immunology. 2015 Feb;144 (2) :271-81.|[2]Revach OY, et al. Overcoming resistance to immunotherapy by targeting CD38 in human tumor explants. Cell Rep Med. 2025 Jul 15;6 (7) :102210.|[3]Chen Q, et al. All-trans-retinoic acid and CD38 ligation differentially regulate CD1d expression and α-galactosylceramide-induced immune responses. Immunobiology. 2015 Jan;220 (1) :32-41.