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2-Undecanone

2-Undecanone is a volatile organic compound, which inhibits the DnaKJE-ClpB bichaperone dependent refolding of heat-inactivated bacterial luciferases. 2-Undecanone inhibits lung tumorigenesis[1][2].

Product Specifications

CAS Number

112-12-9

UNSPSC

12352211

Hazard Statement

H227, H410

Target

Bacterial

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/2-undecanone.html

Purity

99.90

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(CCCCCCCCC)=O

Molecular Formula

C11H22O

Molecular Weight

170.30

Precautions

H227, H410

References & Citations

[1]Melkina OE, et al. Ketones 2-heptanone, 2-nonanone, and 2-undecanone inhibit DnaK-dependent refolding of heat-inactivated bacterial luciferases in Escherichia coli cells lacking small chaperon IbpB. Appl Microbiol Biotechnol. 2017 Jul;101 (14) :5765-5771.|[2]Lou Y, et al. Houttuynia cordata Thunb. and its bioactive compound 2-undecanone significantly suppress benzo (a) pyrene-induced lung tumorigenesis by activating the Nrf2-HO-1/NQO-1 signaling pathway. J Exp Clin Cancer Res. 2019 Jun 7;38 (1) :242.

Shipping Conditions

Room Temperature

Storage Conditions

Store at room temperature, keep dry and cool

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

Human Endogenous Metabolite

Available Sizes

Frequently Asked Questions

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