(Rac) -Zenidolol (hydrochloride)
(Rac) -ICI-118551 ((Rac) -ICI-118551) hydrochloride is a selective β2-adrenergic receptor antagonist. (Rac) -ICI-118551 hydrochloride can inhibit dendrite ramification of hippocampal neurons in a mouse model of Alzheimer's disease[1].
Product Specifications
CAS Number
1217094-53-5
Product Name Alternative
(Rac) -ICI-118551 (hydrochloride)
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/rac-ici-118551-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
CC(NC(C)C)C(O)COC1=CC=C(C)C2=C1CCC2.Cl
Molecular Formula
C17H28ClNO2
Molecular Weight
313.86
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Wu Q, et, al. Blocking beta 2-adrenergic receptor inhibits dendrite ramification in a mouse model of Alzheimer's disease. Neural Regen Res. 2017 Sep;12 (9) :1499-1506.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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