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(Rac) -Zenidolol (hydrochloride)

(Rac) -ICI-118551 ((Rac) -ICI-118551) hydrochloride is a selective β2-adrenergic receptor antagonist. (Rac) -ICI-118551 hydrochloride can inhibit dendrite ramification of hippocampal neurons in a mouse model of Alzheimer's disease[1].

Product Specifications

CAS Number

[1217094-53-5]

Product Name Alternative

(Rac) -ICI-118551 (hydrochloride)

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/rac-ici-118551-hydrochloride.html

Solubility

10 mM in DMSO

Smiles

CC(NC(C)C)C(O)COC1=CC=C(C)C2=C1CCC2.Cl

Molecular Formula

C17H28ClNO2

Molecular Weight

313.86

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]Wu Q, et, al. Blocking beta 2-adrenergic receptor inhibits dendrite ramification in a mouse model of Alzheimer's disease. Neural Regen Res. 2017 Sep;12 (9) :1499-1506.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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