(+) -Adomeglivant
(+) -Adomeglivant ((+) -LY2409021) is a potent and selective glycogenotropin receptor antagonist with glucose-lowering activity. (+) -Adomeglivant reduces fasting blood glucose levels in both healthy subjects and patients with type 2 diabetes. The use of (+) -Adomeglivant can help investigate the mechanisms of hyperglycemia in type 2 diabetes. The antagonistic effect of (+) -Adomeglivant makes it challenging to assess the metabolic consequences of postprandial hyperglycemia[1].
Product Specifications
CAS Number
[872260-19-0]
Product Name Alternative
(+) -LY2409021
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/plus-adomeglivant.html
Smiles
O=C(O)CCNC(C1=CC=C([C@H](OC2=CC(C)=C(C3=CC=C(C(C)(C)C)C=C3)C(C)=C2)CCC(F)(F)F)C=C1)=O
Molecular Formula
C32H36F3NO4
Molecular Weight
555.63
References & Citations
[1]The glucagon receptor antagonist LY2409021 has no effect on postprandial glucose in type 2 diabetes
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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