(S) - (+) -Etomoxir

(S) - (+) -Etomoxir is the S enantiomer of Etomoxir (HY-50202) . Etomoxir is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a), inhibits fatty acid oxidation (FAO) through CPT-1a and inhibits palmitate β-oxidation in human, rat and guinea pig[1].

Product Specifications

CAS Number

[828934-40-3]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Acyltransferase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/s-plus-etomoxir.html

Purity

98.65

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(OCC)[C@]1(OC1)CCCCCCOC2=CC=C(C=C2)Cl

Molecular Formula

C17H23ClO4

Molecular Weight

326.82

Precautions

H302, H315, H319, H335

References & Citations

[1]Scott Richard, et al. Improved synthesis of enantiomerically pure Etomoxir and its 2,4-dinitrophenyl analogue. ARKIVOC (Gainesville, FL, United States) (2004), (10), 118-133