Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Robalzotan (hydrochloride)

Robalzotan hydrochloride (NAD-​299 hydrochloride) is a potent and selective 5-Hydroxytryptamine 1A (5-HT1A) inhibitor. Robalzotan hydrochloride increases the firing rate of 5-HT cells. Robalzotan hydrochloride induces 5-HT1A receptor occupancy. Robalzotan hydrochloride has the potential for the research of a cholinergic deficit in the central -nervous system[1][2][3].

Product Specifications

CAS Number

184674-99-5

Product Name Alternative

NAD-​299 (hydrochloride)

UNSPSC

12352005

Target

5-HT Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/robalzotan-hydrochloride.html

Purity

99.5

Smiles

O=C(C1=C2C[C@@H](N(C3CCC3)C4CCC4)COC2=C(F)C=C1)N.[H]Cl

Molecular Formula

C18H24ClFN2O2

Molecular Weight

354.85

References & Citations

[1]Arborelius L, et al. The 5-HT (1A) receptor antagonist robalzotan completely reverses citalopram-induced inhibition of serotonergic cell firing. Eur J Pharmacol. 1999 Oct 8;382 (2) :133-8.|[2]Farde L, et al. PET-Determination of robalzotan (NAD-299) induced 5-HT (1A) receptor occupancy in the monkey brain. Neuropsychopharmacology. 2000 Apr;22 (4) :422-9. |[3]Hu, Xiao Jing, et al. Modulation of acetylcholine release by serotonergic 5-HT1A and 5-HT1B receptors : a microdialysis study in the awake rat. 2007.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

5-HT1 Receptor; mLAG-3

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Alpha-Hyodeoxycholic Acid-d5
TRC-H998102-1MG 1 mg

Alpha-Hyodeoxycholic Acid-d5

Sign In for Pricing
View Details
Frozen Tissue Sections, Lung
CS518897 5x 5 µm

Frozen Tissue Sections, Lung

Sign In for Pricing
View Details
CD40 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI9F4]
TA807686BM 100 µL

CD40 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI9F4]

Sign In for Pricing
View Details
Podophyllotoxin 4-O-Glucoside
TRC-P681010-5MG 5 mg

Podophyllotoxin 4-O-Glucoside

Sign In for Pricing
View Details
WDR37 (C-term) Rabbit Polyclonal Antibody
AP54541PU-N 400 µL

WDR37 (C-term) Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
P40 (deltaNp63) (Squamous, Basal & Myoepithelial Cell Marker), CF568 conjugate, 0.1mg/mL
BNC682314-100 1x 100 µL

P40 (deltaNp63) (Squamous, Basal & Myoepithelial Cell Marker), CF568 conjugate, 0.1mg/mL

Sign In for Pricing
View Details