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3,4-Diphenyl-5H-furan-2-one

3,4-Diphenyl-5H-furan-2-one is a natural compound isolated from the endophytic fungus Aspergillus flavipes AIL8 derived from the mangrove plant Acanthus ilicifolius. 3,4-Diphenyl-5H-furan-2-one is a derivative of 2,3-diphenyltetrahydrofuran (DPTF), which is a COX-2 inhibitor. 3,4-Diphenyl-5H-furan-2-one can be used as a lead compound for inflammation and pain[1][2].

Product Specifications

CAS Number

5635-16-5

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

COX

Type

Natural Products

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/3-4-diphenyl-5h-furan-2-one.html

Smiles

O=C1OCC(C2=CC=CC=C2)=C1C3=CC=CC=C3

Molecular Formula

C16H12O2

Molecular Weight

236.27

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501

References & Citations

[1]Bai Z Q, et al. New phenyl derivatives from endophytic fungus Aspergillus flavipes AIL8 derived of mangrove plant Acanthus ilicifolius[J]. Fitoterapia, 2014, 95: 194-202.|[2]Singh P, et al. 2, 3-Diphenyltetrahydrofurans (DPTF) -A new class of stereogenic diarylheterocycles as potential COX-2 inhibitors-Computational evaluation of COX-2-DPTF binding behaviour[J]. 2006.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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