What is the catalog number for Bobcat339?

The catalog number for Bobcat339 is HY-111558.

What sizes are available for Bobcat339?

Bobcat339 is available in the following size(s): 5 mg, 10 mM - 1 mL, 10 mg, 25 mg, 50 mg.

How many pack sizes does Bobcat339 come in?

Bobcat339 is available in 5 different pack sizes.

Is Bobcat339 in stock?

Bobcat339 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Bobcat339?

Bobcat339 is manufactured by QuantiMol.

What is the estimated delivery time for Bobcat339?

Estimated delivery time for Bobcat339 is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Bobcat339?

The safety data sheet for Bobcat339 is available here: http://file.medchemexpress.com/batch_PDF/HY-111558/Bobcat339-SDS-MedChemExpress.pdf.

Bobcat339

Bobcat339 is a potent and selective cytosine-based inhibitor of TET enzyme, with IC50s of 33 μM and 73 μM for TET1 and TET2, respectively. Bobcat339 is useful to the field of epigenetics and serves as a starting point for new therapeutics that target DNA methylation and gene transcription[1].

Product Specifications

CAS Number

2280037-51-4

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

DNA Methyltransferase; TET Protein

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bobcat339.html

Purity

99.44

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

NC1=NC(N(C2=CC=CC(C3=CC=CC=C3)=C2)C=C1Cl)=O

Molecular Formula

C16H12ClN3O

Molecular Weight

297.74

Precautions

H302, H315, H319, H335

References & Citations

[1]Chua GNL, et, al. Cytosine-Based TET Enzyme Inhibitors. ACS Med Chem Lett. 2019 Jan 31; 10 (2) : 180-185.|[2]Weirath NA, et al. Small Molecule Inhibitors of TET Dioxygenases: Bobcat339 Activity Is Mediated by Contaminating Copper (II) . ACS Med Chem Lett. 2022 Apr 21;13 (5) :792-798.