Zomepirac

Zomepirac (McN-2783-21-98) is a potent prostaglandin biosynthesis inhibitor. Zomepirac is a non-steroidal anti-inflammatory drug (NSAID) . Zomepirac can cause immune-mediated liver injury[1][2].

Product Specifications

CAS Number

[33369-31-2]

UNSPSC

12352005

Target

PGE synthase

Type

Reference compound

Related Pathways

Immunology/Inflammation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/zomepirac.html

Solubility

10 mM in DMSO

Smiles

O=C(O)CC1=CC(C)=C(C(C2=CC=C(Cl)C=C2)=O)N1C

Molecular Formula

C15H14ClNO3

Molecular Weight

291.73

References & Citations

[1]Min Wang, et al. Hepatic covalent adduct formation with zomepirac in the CD26-deficient mouse. J Gastroenterol Hepatol. 2002 Jan;17 (1) :66-71.|[2]T P Pruss, et al. Evaluation of the analgesic properties of zomepirac. J Clin Pharmacol. 1980 Apr;20 (4) :216-22.