Zomepirac
Zomepirac (McN-2783-21-98) is a potent prostaglandin biosynthesis inhibitor. Zomepirac is a non-steroidal anti-inflammatory drug (NSAID) . Zomepirac can cause immune-mediated liver injury[1][2].
Product Specifications
CAS Number
33369-31-2
UNSPSC
12352005
Target
PGE synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/zomepirac.html
Solubility
10 mM in DMSO
Smiles
O=C(O)CC1=CC(C)=C(C(C2=CC=C(Cl)C=C2)=O)N1C
Molecular Formula
C15H14ClNO3
Molecular Weight
291.73
References & Citations
[1]Min Wang, et al. Hepatic covalent adduct formation with zomepirac in the CD26-deficient mouse. J Gastroenterol Hepatol. 2002 Jan;17 (1) :66-71.|[2]T P Pruss, et al. Evaluation of the analgesic properties of zomepirac. J Clin Pharmacol. 1980 Apr;20 (4) :216-22.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
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