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Zilucoplan (PEG2)

Zilucoplan (PEG2) is a Zilucoplan derivative, where the linker section replaces PEG24 by PEG2. Zilucoplan is a potent complement component 5 (C5) inhibitor[1].

Product Specifications

UNSPSC

12352005

Target

Complement System

Type

Peptides

Related Pathways

Immunology/Inflammation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/zilucoplan-peg2.html

Smiles

CCCCCCCCCCCCCCCC(N[C@H](C(O)=O)CCC(NCCOCCOCCC(NCCCC[C@H](NC([C@@H](NC([C@@H]1CCCN1C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](N(C([C@@H]2CC(NCCCC[C@H](NC(C)=O)C(N[C@@H](C(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC3=CC=CC=C3)C(N2)=O)=O)=O)=O)=O)=O)=O)C)CC(O)=O)=O)C(C)(C)C)=O)CC4=CC=C(O)C=C4)=O)CC5=CNC6=C5C=CC=N6)=O)CCC(O)=O)=O)CC7=CC=C(O)C=C7)=O)=O)C8CCCCC8)=O)C(O)=O)=O)=O)=O

Molecular Formula

C128H190N24O33

Molecular Weight

2593.02

References & Citations

[1]Julien S, et, al. Prevention of Anti-HMGCR Immune-Mediated Necrotising Myopathy by C5 Complement Inhibition in a Humanised Mouse Model. Biomedicines. 2022 Aug 20;10 (8) :2036.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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