Delpacibart
Delpacibart is a humanized IgG1 kappa antibody targeting TFRC. Delpacibart is commonly used for synthesizing AOC drugs such as Delpacibart etedesiran. Delpacibart is commonly used in the study of type 1 myotonic dystrophy (DM1) [1].
Product Specifications
CAS Number
[2653183-66-3]
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
Antibody-Oligonucleotide Conjugates (AOCs) ; Transferrin Receptor
Type
Inhibitory Antibodies
Related Pathways
Antibody-drug Conjugate/ADC Related; Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/delpacibart.html
Purity
98.06
Solubility
10 mM in DMSO
Smiles
[Delpacibart]
Molecular Weight
(144.44 kDa)
Precautions
H302, H315, H319, H335
References & Citations
[1]M. Fowler, et al. 226P Phase 3, randomized, global study assessing efficacy and safety of del-desiran for the treatment of myotonic dystrophy type 1: HARBOR trial design. Neuromuscular Disorders. 2024 104441.68.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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