S-MTC (dihydrochloride)
S-MTC (S-Methyl-L-thiocitrulline) dihydrochloride is a selective type I nitric oxide synthase (NOS) inhibitor.
Product Specifications
CAS Number
209589-59-3
Product Name Alternative
S-Methyl-L-thiocitrulline (dihydrochloride)
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
NO Synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/s-mtc-dihydrochloride.html
Purity
99.00
Solubility
DMSO : 20 mg/mL (ultrasonic; warming)
Smiles
N[C@@H](CCCNC(SC)=N)C(O)=O.[H]Cl.[H]Cl
Molecular Formula
C7H17Cl2N3O2S
Molecular Weight
278.20
Precautions
H302, H315, H319, H335
References & Citations
[1]Law A, et al. Neuroprotective and neurorescuing effects of isoform-specific nitric oxide synthase inhibitors, nitric oxide scavenger, and antioxidant against beta-amyloid toxicity. Br J Pharmacol. 2001 Aug;133 (7) :1114-24.|[2]Zelinski LM, et al. A prolonged nitric oxide-dependent, opioid-mediated antinociceptive effect of hyperbaric oxygenin mice. J Pain. 2009 Feb;10 (2) :167-72.|[3]Wakefield ID, et al. Comparative regional haemodynamic effects of the nitric oxide synthase inhibitors, S-methyl-L-thiocitrulline and L-NAME, in conscious rats. Br J Pharmacol. 2003 Jul;139 (6) :1235-43.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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