S-MTC (dihydrochloride)

S-MTC (S-Methyl-L-thiocitrulline) dihydrochloride is a selective type I nitric oxide synthase (NOS) inhibitor.

Product Specifications

CAS Number

[209589-59-3]

Product Name Alternative

S-Methyl-L-thiocitrulline (dihydrochloride)

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

NO Synthase

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/s-mtc-dihydrochloride.html

Purity

99.00

Solubility

DMSO : 20 mg/mL (ultrasonic; warming)

Smiles

N[C@@H](CCCNC(SC)=N)C(O)=O.[H]Cl.[H]Cl

Molecular Formula

C7H17Cl2N3O2S

Molecular Weight

278.20

Precautions

H302, H315, H319, H335

References & Citations

[1]Law A, et al. Neuroprotective and neurorescuing effects of isoform-specific nitric oxide synthase inhibitors, nitric oxide scavenger, and antioxidant against beta-amyloid toxicity. Br J Pharmacol. 2001 Aug;133 (7) :1114-24.|[2]Zelinski LM, et al. A prolonged nitric oxide-dependent, opioid-mediated antinociceptive effect of hyperbaric oxygenin mice. J Pain. 2009 Feb;10 (2) :167-72.|[3]Wakefield ID, et al. Comparative regional haemodynamic effects of the nitric oxide synthase inhibitors, S-methyl-L-thiocitrulline and L-NAME, in conscious rats. Br J Pharmacol. 2003 Jul;139 (6) :1235-43.