Verazine
Product Specifications
UNSPSC Description
Verazine ((-)-Verazine) is an anti-Fungal Agent that can be found in the dried roots and rhizoma of Veratrum maackii Regel. Verazine causes DNA damage in the cerebellum and cerebral cortex of mice in a dose-dependent manner. Verazine can be used in the study of fungal infections and neurological diseases[1][2].
Target Antigen
Fungal
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/verazine.html
Purity
99.0
Solubility
10 mM in DMSO
Smiles
C[C@]12[C@](CC[C@]1([H])[C@@H](C(CC3)=NC[C@H]3C)C)([H])[C@@](CC=C4C[C@H]5O)([H])[C@@](CC2)([H])[C@]4(CC5)C
Molecular Weight
397.64
References & Citations
[1]Cong Y, et al. Steroidal Alkaloids from Veratrum maackii Regel with Genotoxicity on Brain-Cell DNA in Mice. Helv Chim Acta. 2015, 98(4): 539-545.|[2]Augustin MM, et al. Elucidating steroid alkaloid biosynthesis in Veratrum californicum: production of verazine in Sf9 cells. Plant J. 2015 Jun;82(6):991-1003.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N11911/Verazine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N11911/Verazine-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
14320-81-1
Available Sizes
Curated Selection
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