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GLP-1R agonist 22

GLP-1R agonist 22 (Compound I-135) is an agonist for glucagon-like peptide-1 receptor (GLP-1 receptor), with EC50 of 0.0165 nM[1].

Product Specifications

UNSPSC

12352005

Target

GLP Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/glp-1r-agonist-22.html

Solubility

10 mM in DMSO

Smiles

ClC1=CC(F)=C(COC2=C(C#N)C=C(CCN(CC3=NC4=CC=C(C(O)=O)C=C4N3C[C@@H]5CCO5)[C@H]6C)C6=N2)C=C1

Molecular Formula

C30H27ClFN5O4

Molecular Weight

576.02

References & Citations

[1]Kitamura FY, et al., Fused ring compound having glp-1 receptor agonist effect. WO2024063143A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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