Tubulin polymerization-IN-69
Product Specifications
UNSPSC Description
Tubulin polymerization-IN-69 (compund 6c) significantly inhibits microtubule/tubulin polymerization in vitro (78.3% inhibition) with an IC50 value of 6.53 μM, and rapidly induces apoptotic cell death and G2/M cell cycle arrest in MCF-7 cells[1].
Target Antigen
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tubulin-polymerization-in-69.html
Smiles
O=C(C1=C2C=CC=C1)N(CC3=CN(CCC(NC4=CC=C(S(=O)(NC5=NC=CC=C5)=O)C=C4)=O)N=N3)C2=O
Molecular Weight
531.54
References & Citations
[1]https://www.sciencedirect.com/science/article/abs/pii/S0045206824007326
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-168128/Tubulin-polymerization-IN-69-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-168128/
Clinical Information
No Development Reported
Curated Selection
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