IRAK1 Protein, Active

<strong>IRAK1 Protein, Active</strong>_x000D_ <strong>Catalog number:</strong> B2019385_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 5  µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 59.7 kDa_x000D_ <strong>Supplied as:</strong> Resin_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> −70°C_x000D_ <strong>Keywords:</strong> IRAK1 Protein, Active_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Ngo VN, Young RM, Schmitz R, Jhavar S, Xiao W, Lim KH, Kohlhammer H, Xu W, Yang Y, Zhao H, Shaffer AL, Romesser P, Wright G, Powell J, Rosenwald A, Muller-Hermelink HK, Ott G, Gascoyne RD, Connors JM, Rimsza LM, Campo E, Jaffe ES, Delabie J, Smeland EB, Fisher RI, Braziel RM, Tubbs RR, Cook JR, Weisenburger DD, Chan WC, Staudt LM. Oncogenically active MYD88 mutations in human lymphoma Nature. 2011 Feb 3;470(7332):115-9._x000D_ 2: Landers VD, Wilkey DW, Merchant ML, Mitchell TC, Sokoloski KJ. The Alphaviral Capsid Protein Inhibits IRAK1-Dependent TLR Signaling Viruses. 2021 Feb 27;13(3):377._x000D_ 3: Muruganandam M, Ariza-Hutchinson A, Patel RA, Sibbitt WL Jr. Biomarkers in the Pathogenesis, Diagnosis, and Treatment of Systemic Sclerosis J Inflamm Res. 2023 Oct 17;16:4633-4660._x000D_ 4: Li J, Sun Y, Zhao X, Ma Y, Xie Y, Liu S, Hui B, Shi X, Sun X, Zhang X. Radiation induces IRAK1 expression to promote radioresistance by suppressing autophagic cell death via decreasing the ubiquitination of PRDX1 in glioma cells Cell Death Dis. 2023 Apr 8;14(4):259._x000D_ 5: Li Y, Shah RB, Sarti S, Belcher AL, Lee BJ, Gorbatenko A, Nemati F, Yu H, Stanley Z, Rahman M, Shao Z, Silva JM, Zha S, Sidi S. A noncanonical IRAK4-IRAK1 pathway counters DNA damage-induced apoptosis independently of TLR/IL-1R signaling Sci Signal. 2023 Dec 19;16(816):eadh3449._x000D_ 6: Pereira M, Ramalho T, Andrade WA, Durso DF, Souza MC, Fitzgerald KA, Golenbock DT, Silverman N, Gazzinelli RT. The IRAK1/IRF5 axis initiates IL-12 response by dendritic cells and control of Toxoplasma gondii infection Cell Rep. 2024 Feb 27;43(2):113795._x000D_ 7: Li WW, Fan XX, Xu ZS, Zhu ZX, Zhu ZY, Cao XJ, Pei DS, Wang YZ, Zhang JY, Wang YY, Zheng HX. BLK positively regulates TLR/IL-1R signaling by catalyzing TOLLIP phosphorylation J Cell Biol. 2024 Feb 5;223(2):e202302081._x000D_ 8: Yadav H, Shirumalla RK. Emerging trends in IRAK-4 kinase research Mol Biol Rep. 2023 Sep;50(9):7825-7837._x000D_ 9: Hoyler T, Bannert B, André C, Beck D, Boulay T, Buffet D, Caesar N, Calzascia T, Dawson J, Kyburz D, Hennze R, Huppertz C, Littlewood-Evans A, Loetscher P, Mertz KD, Niwa S, Robert G, Rush JS, Ruzzante G, Sarret S, Stein T, Touil I, Wieczorek G, Zipfel G, Hawtin S, Junt T. Nonhematopoietic IRAK1 drives arthritis via neutrophil chemoattractants JCI Insight. 2022 Jul 8;7(13):e149825._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/37311534">10: Zhang L, Wu JH, Jean-Charles PY, Murali P, Zhang W, Jazic A, Kaur S, Nepliouev I, Stiber JA, Snow K, Freedman NJ, Shenoy SK. Phosphorylation of USP20 on Ser334 by IRAK1 promotes IL-1β-evoked signaling in vascular smooth muscle cells and vascular inflammation J Biol Chem. 2023 Jul;299(7):104911. </a>_x000D_ _x000D_ <strong>Products Related to IRAK1 Protein, Active can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>