miRNA Mimic Negative Control

miRNA Mimics are chemically modified; double-stranded miRNA-like RNA which are designed to copy the functionality of mature endogenous miRNA upon transfection. At the 5'-end; it is synthesized with a partially complementary motif to 3'UTR end of the target gene; which allows the miRNA mimic to specifically bind to the target. Transfection of mimics followed by downstream gene expression analysis or phenotypic analysis; is performed to elucidate the targets and roles of particular miRNAs.