Zilganersen
Zilganersen (ION373) is a glial fibrillary acidic protein (GFAP) inhibitor, an antisense oligonucleotide. Zilganersen can be used in Alexander disease (AxD) research[1][2].
Product Specifications
CAS Number
2305355-56-8
Product Name Alternative
ION373
UNSPSC
12352208
Target
FAP
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/zilganersen.html
Purity
91.43
Solubility
10 mM in DMSO
Smiles
[Zilganersen]
Molecular Formula
C230H320N67O127P19S
Molecular Weight
7060.80
References & Citations
[1]Helm J, et al. Towards Personalized Allele-Specific Antisense Oligonucleotide Therapies for Toxic Gain-of-Function Neurodegenerative Diseases. Pharmaceutics. 2022 Aug 16;14 (8) :1708.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Available Sizes
Frequently Asked Questions
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