Zilganersen

Zilganersen (ION373) is a glial fibrillary acidic protein (GFAP) inhibitor, an antisense oligonucleotide. Zilganersen can be used in Alexander disease (AxD) research[1][2].

Product Specifications

CAS Number

[2305355-56-8]

Product Name Alternative

ION373

UNSPSC

12352208

Target

FAP

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/zilganersen.html

Purity

91.43

Solubility

10 mM in DMSO

Smiles

[Zilganersen]

Molecular Formula

C230H320N67O127P19S

Molecular Weight

7060.80

References & Citations

[1]Helm J, et al. Towards Personalized Allele-Specific Antisense Oligonucleotide Therapies for Toxic Gain-of-Function Neurodegenerative Diseases. Pharmaceutics. 2022 Aug 16;14 (8) :1708.