Suc-Ala-Glu-Pro-Phe-pNA
Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA) is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc[1][2].
Product Specifications
CAS Number
128802-76-6
Product Name Alternative
Suc-AEPF-pNA
UNSPSC
12171500
Target
Biochemical Assay Reagents
Type
Dye Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/suc-ala-glu-pro-phe-pna.html
Purity
99.45
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(N(CCC1)[C@@H]1C(N[C@H](C(NC(C=C2)=CC=C2[N+]([O-])=O)=O)CC3=CC=CC=C3)=O)[C@H](CCC(O)=O)NC([C@H](C)NC(CCC(O)=O)=O)=O
Molecular Formula
C32H38N6O11
Molecular Weight
682.68
References & Citations
[1]Subedi A, et al. Discovery of novel selenium derivatives as Pin1 inhibitors by high-throughput screening. Biochem Biophys Res Commun. 2016 Jun 3;474 (3) :528-533. |[2]Liu C, et al. Imazamethabenz inhibits human breast cancer cell proliferation, migration and invasion via combination with Pin1. Mol Med Rep. 2017 May;15 (5) :3210-3214.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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