Suc-Ala-Glu-Pro-Phe-pNA

Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA) is a chromogenic substrate for the peptidylprolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA can be used to evaluate the inhibitory effect of the target compound on Pin1, and catalytic activity of Pin1, etc[1][2].

Product Specifications

CAS Number

[128802-76-6]

Product Name Alternative

Suc-AEPF-pNA

UNSPSC

12171500

Target

Biochemical Assay Reagents

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/suc-ala-glu-pro-phe-pna.html

Purity

99.45

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(N(CCC1)[C@@H]1C(N[C@H](C(NC(C=C2)=CC=C2[N+]([O-])=O)=O)CC3=CC=CC=C3)=O)[C@H](CCC(O)=O)NC([C@H](C)NC(CCC(O)=O)=O)=O

Molecular Formula

C32H38N6O11

Molecular Weight

682.68

References & Citations

[1]Subedi A, et al. Discovery of novel selenium derivatives as Pin1 inhibitors by high-throughput screening. Biochem Biophys Res Commun. 2016 Jun 3;474 (3) :528-533. |[2]Liu C, et al. Imazamethabenz inhibits human breast cancer cell proliferation, migration and invasion via combination with Pin1. Mol Med Rep. 2017 May;15 (5) :3210-3214.