HS38
HS38 is a potent, selective, and ATP-competitive inhibitor of death-associated protein kinase 1 (DAPK1) and zipper-interacting protein kinase (ZIPK, also called DAPK3), with Kds of 300 nM and 280 nM, respectively. HS38 is also a PIM3 inhibitor with an IC50 of 200 nM. HS38 can be used for the research of smooth muscle related disorders[1].
Product Specifications
CAS Number
[1030203-81-6]
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
DAPK
Type
Reference compound
Related Pathways
Apoptosis
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/hs38.html
Concentration
10mM
Purity
99.91
Solubility
DMSO : 7.14 mg/mL (ultrasonic)
Smiles
CC(SC1=NC(N(C2=CC=CC(Cl)=C2)N=C3)=C3C(N1)=O)C(N)=O
Molecular Formula
C14H12ClN5O2S
Molecular Weight
349.80
Precautions
H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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