rno-let-7i-5p miRNA Mimic

miRNA Mimics are chemically modified, double-stranded miRNA-like RNA which are designed to copy the functionality of mature endogenous miRNA upon transfection. At the 5'-end, it is synthesized with a partially complementary motif to 3'UTR end of the target gene, which allows the miRNA mimic to specifically bind to the target. Transfection of mimics followed by downstream gene expression analysis or phenotypic analysis, is performed to elucidate the targets and roles of particular miRNAs.