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(S) -Renzapride

(S) -Renzapride ((S) -BRL 24924) is the isomer of HY-14147 Renzapride. Renzapride is a 5-HT4 receptor agonist with a Ki value of 115 nM. Renzapride also is a 5HT2b and 5HT3 receptor antagonist. Renzapride can be used for constipation predominant irritable bowel syndrome (C-IBS) study[1][2].

Product Specifications

Product Name Alternative

(S) -BRL 24924

UNSPSC

12352005

Target

5-HT Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/s-renzapride.html

Purity

98.06

Solubility

DMSO : 35 mg/mL (ultrasonic)

Smiles

ClC1=C(N)C=C(OC)C(C(N[C@H]2CCN3CCC[C@H]2C3)=O)=C1

Molecular Formula

C16H22ClN3O2

Molecular Weight

323.82

References & Citations

[1]Camilleri M, et al. Effect of renzapride on transit in constipation-predominant irritable bowel syndrome. Clin Gastroenterol Hepatol. 2004;2 (10) :895-904. |[2]Scarpellini E, et al. Renzapride: a new drug for the treatment of constipation in the irritable bowel syndrome. Expert Opin Investig Drugs. 2008;17 (11) :1663-1670.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

5-HT2 Receptor

Available Sizes

Curated Selection

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