(+) -Syringaresinol

(+) -Syringaresinol, a lignan, is a NFAT transcription factor inhibitor, with an IC50 of 329.4 μM. (+) -Syringaresinol also can be used for the research of lymphocytic leukemia[1][2].

Product Specifications

CAS Number

[21453-69-0]

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

Nuclear Factor of activated T Cells (NFAT)

Type

Natural Products

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/plus-syringaresinol.html

Purity

98.69

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

OC1=C(C=C(C=C1OC)[C@@H]2[C@@]3([C@]([H])(CO2)[C@H](OC3)C4=CC(OC)=C(C(OC)=C4)O)[H])OC

Molecular Formula

C22H26O8

Molecular Weight

418.44

Precautions

H302, H315, H319

References & Citations

[1]Cai XF, et, al. Inhibitory lignans against NFAT transcription factor from Acanthopanax koreanum. Arch Pharm Res. 2004 Jul;27 (7) :738-41.|[2]Badawi MM, et, al. Plant anticancer agents XXVII: Antileukemic and cytotoxic constituents of Dirca occidentalis (Thymelaeaceae) . J Pharm Sci. 1983 Nov;72 (11) :1285-7.